7 Medications That Can Increase Blood Pressure

All adults in the U.S. have Hypertension (high blood pressure). Most of the time, it’s caused by genes and how people live. Some of these are having a history of high blood pressure in your family, being overweight, and getting older. But it can also be caused by kidney disease or certain medicines.

Knowing if any of your medicines could cause your blood pressure to go up is crucial. Talk to your physician about all the medications you take to find out if any of them put you at risk for this. Here are 10 medicines that can make your blood pressure go up.


Nonsteroidal anti-inflammatory drugs (NSAIDs) treat fever, pain, and inflammation. They can be bought without a prescription (OTC) or with a prescription. NSAIDs can increase your blood pressure. One way they do this is by making the body keep salt and water in its cells.

Ibuprofen (Motrin, Advil) may be the NSAID that most often raises blood pressure. Naproxen (Aleve, Naprosyn) and diclofenac (Cambia, Voltaren Arthritis Pain) may have less of an effect on your blood pressure. Celecoxib (Celebrex) is another NSAID, but it works slightly differently than the ones we’ve discussed. Because of this, Celebrex probably doesn’t increase blood pressure as much as ibuprofen or other NSAIDs.

Remember that NSAIDs are in many over-the-counter (OTC) products, even some you might not expect. This includes Advil Cold and Sinus (ibuprofen and pseudoephedrine) and Advil PM (ibuprofen and diphenhydramine), which help you sleep. If you have huge blood pressure, your doctor may tell you to stay away from NSAIDs.


Bupropion is an unusual antidepressant found in Wellbutrin XL and Wellbutrin SR. It works by making the body make more norepinephrine and dopamine. These chemicals could cause high blood pressure.

Even though bupropion rarely causes high blood pressure, your physician will likely check your blood pressure both before and during treatment. And you shouldn’t take certain drugs called monoamine oxidase inhibitors (MAOIs) within 2 weeks of taking Wellbutrin. When these medicines are taken together, they can lead to hazardously high blood pressure.

ADHD Medication

Stimulant medications have Adderall (dextroamphetamine/amphetamine salts) and Ritalin (methylphenidate). They are used to treat ADHD (ADHD). These medicines may cause a small rise in blood pressure. They might do this by making more dopamine and norepinephrine.

Strattera (atomoxetine), another non-stimulant ADHD drug, may raise blood pressure. If you have high blood pressure, coronary artery disease, or other heart problems, talk to your doctor (like a previous heart attack or stroke). Stimulants may be more dangerous if you have one of these health problems.


Steroids, which are what most people call corticosteroids, are used to reduce inflammation in the body. Prednisone and methylprednisolone are two of these (Medrol). They are used to treat many different conditions, such as rheumatoid arthritis, which is an autoimmune disease. High blood pressure is more likely to happen if you use steroids. It’s because they help keep salt and water in the body.

If you take supplements, your doctor may ask you to do blood pressure checks at home. Talk to your physician if your blood pressure is high. They might help you stop safely taking steroids. But if you can’t stop taking steroids, talk to your doctor about other ways to control your blood pressure. Sometimes, you may need to take medicine to lower your blood pressure.


Decongestants, like the ones in Sudafed PE that contain pseudoephedrine and phenylephrine, can help clear up a stuffy nose. They make the blood vessels in your nose smaller, which makes the swelling go down. But making blood vessels smaller in other body parts can cause high blood pressure. Your heart rate may also go up if you take these medicines. If you have high blood pressure, your physician may suggest a different medicine for your blocked nose.


Immunosuppressants are drugs that make your immune system less effective. They are often used to keep the body from dismissing an organ transplant or to treat a flare-up of an autoimmune condition. Some immunosuppressants, however, may raise blood pressure.

Two examples are cyclosporine (Sandimmune) and tacrolimus (Prograf). By narrowing your blood vessels and trying to make your kidneys hold on to salt, these medicines may cause your blood pressure to go up.

If you take cyclosporine or tacrolimus, your doctor will monitor your blood pressure. They will help you decide what to do if your blood pressure is high. Don’t stop taking these medicines until you’ve talked to your doctor or nurse. It can be dangerous to stop them quickly.


Biologics are medicines that are made up of natural substances, like sugars or proteins. They treat many conditions, including those caused by the immune system. But some biological drugs, such as Humira (adalimumab) and Remicade, can cause high blood pressure (infliximab).

If you take a biologic, your doctor will probably examine your blood pressure before and during your treatment. If you get high blood pressure, they will assist you in figuring out how to handle it.

How can you bring your blood pressure down?

Some things you can’t change, like your genes, sex, and age, can make you more probably to have high blood pressure. But you might be able to control other things that can cause high blood pressure. Some of the most crucial things you can do to lower your blood pressure are:

  • They are adopting a DASH diet. Dietary Strategies to Stop High Blood Pressure is what DASH stands for. This diet mainly focuses on fresh fruits and vegetables, while processed foods are eaten less often.
  • Cut down on alcohol. If you drink too much, it can reason your blood pressure to go up. Men shouldn’t drink more than 2 drinks daily, and women shouldn’t drink more than one.
  • Lose weight. Hypertension is linked to having a lot of extra weight. But you might be able to slim down and decrease your blood pressure if you watch what you eat and work out.
  • Aerobic exercise. Working out can help you keep your blood pressure in check. The usual advice is to work out 150 minutes per week. This includes things like walking quickly.